What is Melanotan?
Melanotan is a synthetic peptide designed strictly for research purposes. It is structurally similar to the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH), which binds to melanocortin receptors involved in:
- Skin pigmentation
- Appetite regulation
- Immune response
Two variants exist: Melanotan 1 and Melanotan 2, each with distinct properties and research applications.
Melanotan 1 vs. Melanotan 2
Feature | Melanotan 1 | Melanotan 2 |
Primary Target | MC1R (melanin production) | MC1R, MC3R, MC4R (melanin, appetite, energy balance) |
Duration of Action | Longer half-life, stable effect | A shorter half-life may require more frequent dosing |
Side Effects | Fewer reported in studies | Possible appetite suppression, nausea, flushing |
Research Focus | UV protection, pigmentation studies | Pigmentation, appetite, and weight regulation |
Potency | Lower | Higher |
Mechanism of Action
Melanotan may act by binding to melanocortin receptors (MCRs):
- MC1R – Regulates melanin production in melanocytes, potentially increasing pigmentation.
- MC3R & MC4R – May influence appetite, energy balance, and metabolism.
Through these pathways, Melanotan is studied for pigmentation, weight regulation, and UV protection research.
Potential Research Applications
Preclinical and clinical studies suggest Melanotan may support:
- Pigmentation research – Studying melanin production in skin cells
- Appetite regulation studies – Especially with Melanotan 2 and its effects on MC4R
- UV protection studies – Investigating protective responses to UV exposure
- Energy metabolism research – Examining links to weight management and energy balance
These findings are research-based and not established medical outcomes.
Clinical Research
Some areas of investigation include:
- Skin pigmentation studies – including conditions such as vitiligo
- Appetite & energy regulation – Melanotan 2 has been tested for its role in weight management research
- UV protection research – Early studies suggest a potential protective role for skin exposed to UV radiation
Melanotan and Weight Management
Preliminary findings suggest Melanotan 2 may interact with MC4R receptors, influencing appetite suppression and energy expenditure. This has made it a subject of interest in metabolic and weight regulation research, though much remains under investigation.
FAQs
What is Melanotan used for in research?
It is studied for its effects on pigmentation, appetite regulation, UV protection, and energy balance.
How does Melanotan differ from other peptides?
It specifically targets melanocortin receptors, which regulate melanin and may influence metabolic pathways.
Where can I buy Melanotan online for research
Purerawz Supplements offers high-quality Melanotan-2 Tablets for research purposes, each batch verified by a Certificate of Analysis (COA) confirming identity, purity, and concentration.
Is Melanotan legal?
It is legal to purchase for laboratory research purposes. It is not FDA-approved for human or veterinary use.
Does Melanotan have reported side effects in studies?
Yes, research suggests possible side effects such as flushing, appetite changes, or nausea, particularly with Melanotan 2.
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